Sequences related to the ox pancreatic ribonuclease coding region in the genomic DNA of mammalian species
| Autor: | Chiara Costanzo, Antonella Carsana, Adriana Furia, M. P. Sasso, E Confalone, Heleen J. Breukelman, Marta Palmieri, Jaap J. Beintema |
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| Přispěvatelé: | Breukelman, H. J., Beintema, J. J., Confalone, E., Costanzo, C., Sasso, M. P., Carsana, Antonella, Palmieri, M., Furia, A. |
| Rok vydání: | 1993 |
| Předmět: |
Molecular Sequence Data
Species Specificity Molecular evolution Complementary DNA Gene duplication Genetics Coding region Animals Ribonuclease Amino Acid Sequence Cloning Molecular Molecular Biology Gene Ecology Evolution Behavior and Systematics Conserved Sequence Mammals biology Base Sequence DNA Ribonuclease Pancreatic genomic DNA Multigene Family biology.protein Pancreatic ribonuclease Cattle |
| Zdroj: | Journal of molecular evolution. 37(1) |
| ISSN: | 0022-2844 |
| Popis: | Mammalian pancreatic ribonucleases form a family of homologous proteins that has been extensively investigated. The primary structures of these enzymes were used to derive phylogenetic trees. These analyses indicate that the presence of three strictly homologous enzymes in the bovine species (the pancreatic, seminal, and cerebral ribonucleases) is due to gene duplication events which occurred during the evolution of ancestral ruminants. In this paper we present evidence that confirms this finding and that suggests an overall structural conservation of the putative ribonuclease genes in ruminant species. We could also demonstrate that the sequences related to ox ribonuclease coding regions present in genomic DNA of the giraffe species are the orthologues of the bovine genes encoding the three ribonucleases mentioned above. |
| Databáze: | OpenAIRE |
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