Effects of Various Commercially Available Enrichment Options on Handling and Chronic Stress Markers in Female ICR Mice
| Autor: | R'nld R Wheeler, Debra L. Hickman, Jessica L Peveler, Christine A Boehm, Melissa P. Swan |
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| Rok vydání: | 2019 |
| Předmět: |
Mice
Inbred ICR 0303 health sciences Environmental enrichment business.industry Physiology Negative control Animal Welfare Housing Animal Mice 03 medical and health sciences 0302 clinical medicine Laboratory Animal Science Stress Physiological Husbandry Animals Medicine Female Animal Science and Zoology Chronic stress Animal Husbandry business Biomarkers 030217 neurology & neurosurgery Icr mice 030304 developmental biology |
| Zdroj: | Journal of the American Association for Laboratory Animal Science. 58:119-125 |
| ISSN: | 1559-6109 |
| Popis: | Although social housing of mice generally is preferred, mice must be individually housed in some situations. In these cases, enhanced attention to environmental enrichment is encouraged, but few studies assess the wellbeing of mice provided various enrichments. In this study, we used female ICR mice to evaluate enrichment strategies that encouraged natural behaviors including foraging, exercise, sheltering, and socialization. After 3 mo of exposure to the assigned enrichment strategy, wellbeing was assessed by evaluating behavioral and physiologic differences between groups. The results suggested that the use of red-tinted igloos may decrease markers of mouse wellbeing. However, none of the selected strategies yielded measures of wellbeing indicating improvement as compared to individually housed mice with no enrichment (negative control). Furthermore, measures were not significantly different between paired mice and individually housed mice with no enrichment. |
| Databáze: | OpenAIRE |
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