C-F bond substitution via aziridinium ion intermediates
| Autor: | Annika M. Träff, Göran Hilmersson, Mario Janjetovic |
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| Rok vydání: | 2015 |
| Předmět: |
Tris
Substitution reaction Substitution (logic) Metals and Alloys chemistry.chemical_element General Chemistry Ring (chemistry) Photochemistry Medicinal chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Ion chemistry.chemical_compound chemistry Nucleophile Materials Chemistry Ceramics and Composites Lanthanum |
| Zdroj: | Chemical communications (Cambridge, England). 51(68) |
| ISSN: | 1364-548X |
| Popis: | A mild and distinct methodology for instantaneous β-amino fluoride substitution mediated by La[N(SiMe3)2]3 has been developed. The reaction proceeds via a reactive aziridinium ion intermediate, which readily reacts with various nucleophiles. This allows the use of fluorine as a modular functionality and further expands the role of aziridinium ions in organic synthesis. |
| Databáze: | OpenAIRE |
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