Improvement of Two-Stage Centrifugal Blood Pump for Cardiopulmonary Support System and Evaluation of Anti-Hemolysis Performance
| Autor: | Tomonori Tsukiya, Toratarou Takemika, Yoshinobu Tsujimoto, Hironori Horiguchi, Takeshi Nomoto |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Mechanical Engineering medicine.medical_treatment Oxygenation Condensed Matter Physics Centrifugal pump medicine.disease Cannula Thrombosis Industrial and Manufacturing Engineering Hemolysis law.invention Blood pump law Internal medicine Artificial heart medicine Extracorporeal membrane oxygenation Cardiology business |
| Zdroj: | International Journal of Fluid Machinery and Systems. 8:1-12 |
| ISSN: | 1882-9554 |
| DOI: | 10.5293/ijfms.2015.8.1.001 |
| Popis: | In cardiopulmonary support systems with a membrane oxygenation such as a percutaneous cardiopulmonary support (PCPS) or an extracorporeal membrane oxygenation (ECMO), blood pumps need to generate the pressure rise of approximately 200mmHg or higher, due to the high hydraulic resistances of the membrane oxygenation and of the cannula tubing. In order to realize the blood pump with higher pressure rise, higher anti-hemolysis and thrombosis performances, the development of novel centrifugal blood pump composed of two-stage has been conducted by the authors. In the present paper, effective attempts to decrease the wall shear stress and to suppress the stagnation are introduced for the prevention of hemolysis and thrombosis in blood pumps. The hemolysis test was also carried out and it was clarified that the decrease of wall shear stress is effective as a guideline of design of blood pumps for improving the anti-hemolysis performance. Keywords: Centrifugal Pump, Artificial Heart, Blood, Hemolysis, Thrombosis |
| Databáze: | OpenAIRE |
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