Postauricular injection of methylprednisolone sodium succinate as a salvage treatment for refractory sudden sensorineural hearing loss
| Autor: | Bingliang Ma, Jue Xu, Longjiang Lan, Gang Ren, Qi Zhang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Hearing Loss Sensorineural Salvage treatment Salvage therapy 030204 cardiovascular system & hematology Methylprednisolone Dexamethasone 03 medical and health sciences 0302 clinical medicine Refractory Interquartile range medicine Humans 030212 general & internal medicine Methylprednisolone Hemisuccinate Glucocorticoids Retrospective Studies Salvage Therapy business.industry Retrospective cohort study General Medicine Surgery Treatment Outcome Sudden sensorineural hearing loss Corticosteroid Methylprednisolone sodium succinate business |
| Zdroj: | Irish journal of medical science. 190(3) |
| ISSN: | 1863-4362 |
| Popis: | Postauricular steroid administration has been popular for treating sudden sensorineural hearing loss. However, there are few reports on its use in patients with refractory sudden sensorineural hearing loss (RSSNHL). The objective of this study was to investigate the therapeutic efficacy of postauricular steroid injection as a salvage treatment for RSSNHL patients. This retrospective study enrolled 63 RSSNHL patients between January 2016 and January 2019. Thirty-three patients of them who have been divided into the treatment group received postauricular methylprednisolone sodium succinate injection. The remaining 30 patients who formed the control group did not receive any steroid as a salvage therapy. Improvements in hearing were evaluated between pre-salvage therapy and 3 months follow-up after salvage therapy. The median hearing gain in PTA was 9.88 dB HL (quartile range 7.58, 18.65) in the treatment group and 0.90 dB HL (quartile range 0.00, 4.90) in the control group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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