Indocyanine green-mediated photothermal therapy in treatment of chronic periodontitis: A clinico-microbiological study
| Autor: | Alefiya Mamajiwala, Ayushya Warang, Chetan Purushottam Raut, Kunal Sunder Sethi, Bhagyashree Kohale |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
030103 biophysics medicine.medical_specialty indocyanine green photothermal therapy scaling and root planing medicine.medical_treatment Bleeding on probing Photodynamic therapy Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Scaling and root planing Internal medicine medicine Periodontitis business.industry 030206 dentistry Photothermal therapy medicine.disease Chronic periodontitis lcsh:RK1-715 Clinical trial chemistry photodynamic therapy lcsh:Dentistry Periodontics Original Article medicine.symptom business Indocyanine green |
| Zdroj: | Journal of Indian Society of Periodontology Journal of Indian Society of Periodontology, Vol 22, Iss 3, Pp 221-227 (2018) |
| ISSN: | 0972-124X |
| Popis: | Background: Photodynamic therapy (PDT) has developed as an alternative treatment modality in periodontitis patients. Different photosensitizers used over the years have shown contradictory results. Thus, recently indocyanine green (ICG)-mediated photothermal therapy has emerged for the treatment of chronic periodontitis. Aim: The present study aimed at comparing and evaluating the effects of photothermal therapy using ICG in the treatment of chronic periodontitis with scaling and root planing (SRP). Materials and Methods: This was a randomized, controlled, clinical trial where fifty participants were equally divided into two groups, i.e., control group (SRP) and test group (SRP + photothermal therapy). Clinical parameters were evaluated at baseline and 6-month follow-up. These were plaque index (PI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL). Microbiological analysis of plaque sample was also done to check for anaerobic mixed flora. Results: Significant reduction was seen in PD, CAL, and BOP in the test group as compared to control group after 6 months (P < 0.05). However, intergroup comparison of PI showed nonsignificant results (P > 0.05). Anaerobic culture of plaque samples of test group also revealed a significant reduction of microorganisms in comparison with control group. Conclusion: ICG-mediated photothermal therapy can act as an alternative to antimicrobial PDT as an adjunct to SRP in the treatment of chronic periodontitis. |
| Databáze: | OpenAIRE |
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