The role of the PLR–NLR combination in the prediction of the presence of Helicobacter pylori and its associated complications
| Autor: | Mehmet Fettah Arikan, Ertuğrul Kayaçetin, Ihsan Ates, Nesrin Turhan, Gulden Aydog, Volkan Gökbulut, Mustafa Kaplan, Mahmut Yüksel |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Chronic gastritis lymphocyte intestinal metaplasia Gastroenterology 03 medical and health sciences 0302 clinical medicine Atrophy Internal medicine Biopsy medicine lcsh:RC799-869 Risk factor Helicobacter pylori medicine.diagnostic_test biology business.industry Esophagogastroduodenoscopy neutrophil Intestinal metaplasia medicine.disease biology.organism_classification 030220 oncology & carcinogenesis lcsh:Diseases of the digestive system. Gastroenterology 030211 gastroenterology & hepatology Gastritis medicine.symptom business |
| Zdroj: | The Saudi Journal of Gastroenterology, Vol 24, Iss 5, Pp 294-300 (2018) |
| ISSN: | 1319-3767 |
| DOI: | 10.4103/sjg.sjg_29_18 |
| Popis: | Background/Aim: The aim of this study was to investigate the role of the platelet-to-lymphocyte ratio (PLR)–neutrophil-to-lymphocyte ratio (NLR) combination, in the prediction of the presence of Helicobacter pylori (HP) and its associated complications in the gastrointestinal system. Patients and Methods: In all, 1289 patients who underwent esophagogastroduodenoscopy and biopsy for HP were included in the study. Results: The ratio of patients with moderate and severe chronic gastritis was higher in HP (+) group than HP (−) group. The ratio of patients with levels 1–3 atrophy and intestinal metaplasia was higher in HP (+) group. Compared with HP (−) group, HP (+) had higher PLR and NLR levels. The ratio of HP (+) patients was higher in high-risk group compared with low- and medium-risk groups. HP invasion stage, the intestinal metaplasia level, and the ratio of patients with atrophy level “3” were higher in high-risk group compared with low- and medium-risk groups. Regression analysis showed that the PLR–NLR combination was an independent risk factor for both HP presence and moderate and severe chronic gastritis. Conclusion: We found the PLR–NLR combination to be a good predictor of HP presence and gastrointestinal complications associated with HP. |
| Databáze: | OpenAIRE |
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