Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation
| Autor: | Marius Locke, Richard E. Klabunde, Sigrid E. Ianuzzo, William A. Anderson, C. David Ianuzzo |
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| Rok vydání: | 1996 |
| Předmět: |
Male
Time Factors Physiology medicine.medical_treatment Ischemia Hemodynamics Dissection (medical) Physiology (medical) medicine.artery medicine Animals Thoracodorsal artery Sheep business.industry Latissimus dorsi muscle Skeletal muscle Anatomy medicine.disease Electric Stimulation Microspheres medicine.anatomical_structure medicine.symptom business Blood Flow Velocity Cardiomyoplasty Muscle Contraction Muscle contraction |
| Zdroj: | Journal of Applied Physiology. 81:2365-2372 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/jappl.1996.81.6.2365 |
| Popis: | Klabunde, Richard E., William A. Anderson, Marius Locke, Sigrid E. Ianuzzo, and C. David Ianuzzo. Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation. J. Appl. Physiol. 81(6): 2365–2372, 1996.—Latissimus dorsi muscle (LDM) regional blood flows were determined in anesthetized goats by using colored microspheres under noncontracting and contracting conditions, either before or after 8–10 wk of chronic muscle stimulation. Surgical dissection of the LDM, leaving only the thoracodorsal artery to supply the muscle, did not alter regional noncontracting blood flows but significantly reduced the normal hyperemic response to muscle contraction in muscle regions (posterior-medial) furthest from the entrance of the thoracodorsal artery. Eight to 10 wk after acute muscle dissection, posterior-medial hyperemic flows were restored. Chronic stimulation of the LDM for 8–10 wk, in either dissected or nondissected muscles, did not alter regional blood flows in noncontracting muscle; however, it significantly reduced hyperemic flows in all muscle regions, although capillary density was increased and the muscle was transformed into a predominantly type I fiber type. These results, coupled with data from previous experiments, suggest that the muscle damage observed in the posterior-medial regions of the LDM after surgical dissection and chronic stimulation may be related to reduced hyperemic flow responses caused by surgical isolation of the muscle. |
| Databáze: | OpenAIRE |
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