Immunosensing using nanoparticles
| Autor: | Claudio Parolo, Alfredo de la Escosura-Muñiz, Arben Merkoçi |
|---|---|
| Přispěvatelé: | Ministerio de Ciencia e Innovación (España) |
| Rok vydání: | 2010 |
| Předmět: |
Materials science
Surface impedances Mechanical Engineering Nanoparticle Nanotechnology Quartz crystal microbalance Clinical analysis Condensed Matter Physics Future applications Fluorescence spectroscopy Nanomaterials Transducer surface Transducer Materials Science(all) Mechanics of Materials Optical tunability Safety and securities Surface impedance Biosensing systems General Materials Science Surface plasmon resonance Electrochemical techniques Biosensor |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Recercat. Dipósit de la Recerca de Catalunya Recercat: Dipósit de la Recerca de Catalunya Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| ISSN: | 1369-7021 |
| DOI: | 10.1016/s1369-7021(10)70125-5 |
| Popis: | 11 páginas, 9 figuras. Immunosensing technology is taking advantage of the lastest developments in materials science and inparticular from the nanomaterials field. Because of their unprecedented optical tunability as well as electrical and electrochemical qualities, we are seeing significant developments in the design of novel immunoassays; various conventional optical and electrical platforms which allow for future applications in several fields are being used. Properties of nanoparticles such as light absorption and dispersion are bringing interesting immunosensing alternatives. Nanoparticles are improving the sensitivity of existing techniques used for protein detection in immunoassays based on Surface Plasmon Resonance, Quartz Crystal Microbalance, Fluorescence spectroscopy etc. Electrochemical techniques are also taking advantage of electrical properties of nanoparticles. Redox properties of metal based nanoparticles, surface impedance change and conductance changes once nanoparticles are present as labelling tags or modifiers of transducer surfaces are also improving the technology. In most of the examples nanoparticle based biosensing systems are being offered as excellent screening and superior alternatives to existing conventional strategies/assays with interest for fields in clinical analysis, food quality, safety and security. We acknowledge funding from MEC for the projects MAT2008-03079/ NAN, CSD2006-00012-‘‘NANOBIOMED’’- (Consolider-Ingenio-2010) and the JdC scholarship (A.de la Escosura-Muñiz). |
| Databáze: | OpenAIRE |
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