An ongoing research for evaluation of treatment with BMPs or AGFs in long bone non-union: Protocol description and preliminary results
| Autor: | Marco d’Imporzano, Giorgio Maria Calori, Walter Albisetti, Mario D’Avino, L. Tagliabue, Giovanni Peretti |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Bone Regeneration Bone Morphogenetic Protein 7 Long bone Bone morphogenetic protein Non union medicine Humans Fractures Malunited General Environmental Science Protocol (science) Tissue Engineering Platelet-Rich Plasma business.industry Gold standard Middle Aged Autologous bone Surgery Bone morphogenetic protein 7 Treatment Outcome medicine.anatomical_structure Platelet-rich plasma Bone Morphogenetic Proteins General Earth and Planetary Sciences Female business |
| Zdroj: | Injury. 37:S43-S50 |
| ISSN: | 0020-1383 |
| DOI: | 10.1016/j.injury.2006.08.023 |
| Popis: | Treatment of long bone non-union (NU) continues to be a challenging task for the trauma surgeon often resulting in unsatisfactory results and long-term morbidity. Whilst autologous bone grafting remains the gold standard of treatment of these difficult cases, recently, due to the advances made in tissue engineering techniques, other alternatives have become available. In this study we report our preliminary results of treating long bone non-unions using either bone morphogenetic protein-7 (BMP-7) or platelet rich plasma (PRP) concentrations. Twenty-nine cases have entered this study thus far. Preliminary results indicate that BMP-7 is more efficacious that PRP as there was a significant failure rate of 6.2% versus 38.5% between BMP-7 and PRP, respectively. |
| Databáze: | OpenAIRE |
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