Initial studies on a novel filtering-type intra-vas device in male dogs
| Autor: | Chun-you Chen, Qing-ling Du, Xun-bin Huang, Jie-ling Zhou, Jinping Suo, Ji-yun Shen |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
musculoskeletal diseases Semen Beagle Andrology Dogs Vas Deferens Testis Carnivora medicine Animals Epididymis Contraceptive Devices Male business.industry Vas deferens Obstetrics and Gynecology musculoskeletal system Spermatozoa Sperm Nanostructures medicine.anatomical_structure Reproductive Medicine Male genital duct Implant business Copper Filtration |
| Zdroj: | Contraception. 81:350-354 |
| ISSN: | 0010-7824 |
| DOI: | 10.1016/j.contraception.2009.10.012 |
| Popis: | Background To relieve the side effects induced by the complete obstruction of the vas deferens, we created a filtering-type intra-vas device (IVD) which is made of materials composed of nano-SiO 2 -copper complex cross-linking polymer composites. Study Design Eight male beagle dogs were grouped into nonimplanted control group and IVD-implanted group. We tested the efficacy of the sperm filtering effect of the new IVD material for 12 months and examined the influence of the IVD materials on the cells of the vas deferens, epididymis and testis. Results The densities of sperm were reduced significantly after the IVD was implanted; no motile sperm were found after the third month. No obvious morphological changes were found in the cells of the vas deferens, epididymis and testis in the IVD-implanted group. Conclusions The filtering-type nano-SiO 2 -copper complex/polymer composite IVD is able to filter the sperm of the male dogs, and the IVD material did not cause obvious damage to the cells of the male reproductive organs after 1 year of implantation. |
| Databáze: | OpenAIRE |
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