Environmental radiation alters the gut microbiome of the bank vole Myodes glareolus
| Autor: | James T. Morton, Rob Knight, Anton Lavrinienko, Tapio Mappes, Eugene Tukalenko, Luke R. Thompson, Phillip C. Watts, Anders Pape Møller, Timothy A. Mousseau |
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| Přispěvatelé: | Centre of Excellence in Biological interactions (CoE), University of Helsinki-Universität Zürich [Zürich] = University of Zurich (UZH)-University of Jyväskylä (JYU), Ecologie Systématique et Evolution (ESE), Université Paris-Sud - Paris 11 (UP11)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS), Howard Hughes Medical Institute [Chevy Chase] (HHMI), Howard Hughes Medical Institute (HHMI) |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
16S Technology metsämyyrä Firmicutes suolistomikrobisto 030106 microbiology Microbial metabolism gut microbiome Zoology Environmental pollution Gut flora Brief Communication Microbiology säteilybiologia 03 medical and health sciences Microbial ecology RNA Ribosomal 16S Genetics Animals Microbiome bank vole Life Below Water Ecology Evolution Behavior and Systematics [SDV.EE]Life Sciences [q-bio]/Ecology environment Ribosomal biology Bacteria Bacteroidetes Arvicolinae säteily Biological Sciences biology.organism_classification Gastrointestinal Microbiome Bank vole 030104 developmental biology Chernobyl Nuclear Accident 13. Climate action environmental radionuclides RNA Carbohydrate Metabolism Environmental Sciences Radioactive Pollutants |
| Zdroj: | The ISME journal, vol 12, iss 11 The ISME Journal ISME Journal ISME Journal, Nature Publishing Group, 2018, 12 (11), pp.2801-2806. ⟨10.1038/s41396-018-0214-x⟩ |
| ISSN: | 1751-7362 1751-7370 |
| DOI: | 10.1038/s41396-018-0214-x⟩ |
| Popis: | International audience; Gut microbiota composition depends on many factors, although the impact of environmental pollution is largely unknown. We used amplicon sequencing of bacterial 16S rRNA genes to quantify whether anthropogenic radionuclides at Chernobyl (Ukraine) impact the gut microbiome of the bank vole Myodes glareolus. Exposure to elevated levels of environmental radionuclides had no detectable effect on the gut community richness but was associated with an almost twofold increase in the Firmicutes:Bacteroidetes ratio. Animals inhabiting uncontaminated areas had remarkably similar gut communities irrespective of their proximity to the nuclear power plant. Hence, samples could be classified to high-radiation or low-radiation sites based solely on microbial community with >90% accuracy. Radiation-associated bacteria had distinct inferred functional profiles, including pathways involved in degradation, assimilation and transport of carbohydrates, xenobiotics biodegradation, and DNA repair. Our results suggest that exposure to environmental radionuclides significantly alters vertebrate gut microbiota. |
| Databáze: | OpenAIRE |
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