ACQUIRED IMMUNODEFICIENCY SYNDROME WITH SEVERE GASTROINTESTINAL MANIFESTATIONS IN HAITI
| Autor: | P Drotman, A. C. Laroche, Jean-Marie Dupuy, R Mandeville, Arnoux E, C. Pean-Guichard, Malebranche R, P.H Morisset, Thomas A. Seemayer, Guerin Jm, Elie R, Gerard Pierre, Thomas J. Spira |
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| Rok vydání: | 1983 |
| Předmět: |
Adult
Diarrhea Male Tuberculosis Adolescent Fever Gastrointestinal Diseases Congenital cytomegalovirus infection Cutaneous anergy Cell Count Lymphocyte proliferation Immune system Acquired immunodeficiency syndrome (AIDS) Candida albicans Esophagitis Humans Medicine Acquired Immunodeficiency Syndrome Pneumocystis business.industry Body Weight T-Lymphocytes Helper-Inducer General Medicine Middle Aged medicine.disease Haiti Coccidia Pneumocystis carinii Chronic Disease Immunology Female medicine.symptom business |
| Zdroj: | The Lancet. 322:873-878 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(83)90868-1 |
| Popis: | 29 patients (19 males and 10 females) in Haiti were diagnosed as having acquired immunodeficiency syndrome. Their clinical presentation was characterised by unexplained chronic diarrhoea, prolonged fever, extreme weight loss, anorexia, and severe infections. The infectious agents included: Candida albicans (27 patients), Mycobacterium tuberculosis (7 patients), Cryptosporidium (11 patients), Pneumocystis carinii (2 patients), cytomegalovirus (4 patients), and herpes virus (3 patients). In 1 woman Kaposi's sarcoma developed during the course of her disease. Immunological studies of 20 patients revealed profound cell-mediated immune deficiency with cutaneous anergy, marked decrease in the number of T helper cells, and impairment of lymphocyte proliferation. 18 patients died. |
| Databáze: | OpenAIRE |
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