Systemic lupus erythematosus complicating autoimmune pulmonary alveolar proteinosis that was worsened by immunosuppressive therapy
| Autor: | Reika Maezawa, R Hanaoka, Takeshi Fukuda, J. Nagasawa, Kazuhiro Kurasawa, Takayoshi Owada |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
biology business.industry medicine.medical_treatment Granulocyte-Macrophage Colony-Stimulating Factor Immunosuppression Pulmonary Alveolar Proteinosis female genital diseases and pregnancy complications Autoimmune Diseases Rheumatology Autoimmune pulmonary alveolar proteinosis Glucocorticoid therapy Immunology medicine biology.protein Humans Lupus Erythematosus Systemic Female Antibody skin and connective tissue diseases business Immunosuppressive Agents Autoantibodies |
| Zdroj: | Lupus. 22:1060-1063 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1177/0961203313498798 |
| Popis: | A 26-year-old Japanese woman developed autoimmune pulmonary alveolar proteinosis (PAP) during glucocorticoid therapy for systemic lupus erythematosus (SLE). Intensive immunosuppressive therapy worsened the PAP. De-escalation of immunosuppressive therapy improved the PAP. Autoimmune PAP is rarely associated with systemic autoimmune diseases, and the present case is the first case of autoimmune PAP associated with SLE. Moreover, the present case suggests that immunosuppressive therapy should be avoided or used carefully for the treatment of patients with anti-GM-CSF antibody, such as those with autoimmune PAP. |
| Databáze: | OpenAIRE |
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