Alexey Khodjakov: Diving into the mitotic apparatus

Autor:	Caitlin Sedwick
Rok vydání:	2012
Předmět:	Spindle checkpoint Kinetochore Mitotic spindle apparatus Art history Cell Biology Anatomy News Biology Mitosis People & Ideas Mitotic apparatus Spindle pole body Spindle apparatus
Zdroj:	The Journal of Cell Biology
ISSN:	1540-8140 0021-9525
Popis:	Situated at either end of the animal mitotic spindle, centrosomes are one of the most prominent and visually striking features of the mitotic apparatus. But what, exactly, is their function in cell division? And how is the mitotic spindle organized in dividing cells? Alexey Khodjakov PHOTO COURTESY OF IRINA TIKHONENKO AND MICHAEL KOONCE Alexey Khodjakov has been grappling with such questions since he was a graduate student in Russia. Using advanced microscopy techniques including laser ablation (1) and 3D particle tracking (2), Khodjakov has delved deeply into the organization of the mitotic apparatus (3, 4) and its various components (5), making big splashes in the field along the way. We called him at his laboratory at the Wadsworth Institute in Albany, New York, to learn more about his personal and professional explorations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd342e01a27f541087f8b70c77f8a4c9 https://doi.org/10.1083/jcb.1976pi Zobrazit plný text záznamu