Piloting home infusions of Tysabri (natalizumab): a randomised crossover trial
| Autor: | Jon Karnon, Lynette Cusack, Kerisha Naidoo, Lorraine Simon, Anne Thomas, Kevin Webb, Paul Georgiou, Tim Schultz, Mahasen Juaton |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
lcsh:R5-920
medicine.medical_specialty Health (social science) Sociology and Political Science Adult patients home infusion business.industry Health Policy Multiple sclerosis multiple sclerosis medicine.disease Crossover study patient centred care natalizumab Natalizumab Ambulatory care Emergency medicine Usual care Health care medicine lcsh:Medicine (General) business medicine.drug |
| Zdroj: | International Journal of Integrated Care, Vol 19, Iss 4 (2019) |
| ISSN: | 1568-4156 |
| DOI: | 10.5334/ijic.s3617 |
| Popis: | We developed a new model of care for home infusions of natalizumab for people with multiple sclerosis. The new model of care was then tested in a pilot study comparing home infusions of natalizumab with usual care (attendance in an ambulatory care day units) using an AB/BA randomised crossover trial. In addition to testing feasibility and safety of home infusions for people with natalizumab compared to usual care, we investigated if: (i) home infusions of natalizumab are acceptable to patients and healthcare staff, (ii) home infusions of natalizumab are as effective in treating symptoms, and (iii) home infusions of natalizumab are cost effective? There were 37 stable adult patients (at least 6 prior natalizumab infusions and assessed as safe by their neurologist) randomised to an AB or BA trial arm. After 3 infusions, patients crossed over to the alternate treatment for another 3 infusions. |
| Databáze: | OpenAIRE |
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