Hydroxyzine and metabolites as a source of interference in carbamazepine particle-enhanced turbidimetric inhibition immunoassay (PETINIA)
| Autor: | Mustapha Moulsma, Gisèle Lardet, François Parant, Marie Claude Gagnieu |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Norchlorcyclizine Pharmacology Cross Reactions Turbidimetric inhibition immunoassay Therapeutic index Nephelometry and Turbidimetry medicine Humans Pharmacology (medical) Hydroxyzine Immunoassay Chromatography Epilepsy medicine.diagnostic_test Chemistry Reproducibility of Results Carbamazepine Cetirizine Psychotic Disorders Histamine H1 Antagonists Anticonvulsants Oxatomide Drug Monitoring Drug Overdose medicine.drug |
| Zdroj: | Therapeutic drug monitoring. 27(4) |
| ISSN: | 0163-4356 |
| Popis: | A 32-year-old epileptic patient with a lengthy history of multiple-drug abuse and psychotic disorders was found to have an elevated serum carbamazepine concentration of 40.5 mg/L (therapeutic range 4-12 mg/L) using particle-enhanced turbidimetric inhibition immunoassay (PETINIA). Serum reanalysis by LC-DAD revealed only high hydroxyzine (HDZ) concentration (HDZ = 0.55 mg/L; therapeutic range |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|