Comparison of diameter-based and image-based measures of surface area from gross placental pathology for use in epidemiologic studies
| Autor: | Carol J. R. Hogue, Deborah L. Conway, Carolyn Drews-Botsch, Alexa A. Freedman, Carmen J. Marsit, Augustine Rajakumar, Donald J. Dudley, Halit Pinar, Alicia K. Smith, Katie Labgold, Radek Bukowski, Michael W. Varner, Lauren M. Kipling, Robert L. Goldenberg |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Surface (mathematics) Placenta Abnormal shapes Article 03 medical and health sciences 0302 clinical medicine Pregnancy Placental pathology Humans Medicine Fetal Death 030219 obstetrics & reproductive medicine business.industry Reproducibility of Results Obstetrics and Gynecology Organ Size Stillbirth Confidence interval 030104 developmental biology Reproductive Medicine Female business Nuclear medicine Live Birth Image based Developmental Biology |
| Zdroj: | Placenta. 69:82-85 |
| ISSN: | 0143-4004 |
| Popis: | Placental surface area is often estimated using diameter measurements. However, as many placentas are not elliptical, we were interested in the validity of these estimates. We compared placental surface area from images for 491 singletons from the Stillbirth Collaborative Research Network (SCRN) Study (416 live births, 75 stillbirths) to estimates obtained using diameter measurements. Placental images and diameters were obtained from pathologic assessments conducted for the SCRN Study and images were analyzed using ImageJ software. On average, diameter-based measures underestimated surface area by −5.58% (95% confidence interval: −30.23, 19.07); results were consistent for normal and abnormal shapes. The association between surface area and birthweight was similar for both measures. Thus, diameter-based surface area can be used to estimate placental surface area. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect