IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study

Autor: Kevin M Gallagher, E. Zimmermann, Eric Edison, Sacha Moore, Sinan Khadhouri, John S. McGrath, Arjun Nambiar, V. Kasivisvanathan, Kenneth R MacKenzie, Taimur T. Shah, Matthew Jefferies, Graeme MacLennan, Chuanyu Gao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Surgery Protocols
ISSN: 2468-3574
Popis: Aim: A contemporary evaluation of current urological practices, and assessment of the prevalence of urinary tract cancers, in patients referred to secondary care with suspected urinary tract cancer; to allow recommendation in cancer diagnosis pathways that may improve patient experience, minimize invasive and unnecessary investigations, reduce waste of resources and optimize use of the most appropriate tests. Patients: Any patient referred with visible, nonvisible haematuria or nonhaematuria for suspected urothelial cancer, excluding those with previous urological cancer or those who are unable to undergo a cystoscopy. Outcomes: Prevalence of urological cancers in patients referred for suspected urothelial cancer as confirmed on flexible cystoscopy, imaging and/or further cytopathological evaluation. Sensitivity, specificity, positive and negative predictive value of different imaging modalities in the diagnosis of different urothelial cancers. Identification of patient factors associated with different types of urothelial cancer. Costeffectiveness of different diagnostic strategies for diagnosis of bladder and upper tract cancer. Study design: Prospective multicentre observational cohort study carried out in UK, European and non-European International Urological Secondary care centres. Methods Patient data will be collected from secondary care centres that evaluate patients with suspected urinary tract cancer and have the ability for cystoscopy to be carried out. Participating collaborators will need to have access to cystoscopy, and will complete a summary sheet of the normal practice currently used at their site for investigation of suspected urothelial cancer. A set data collection period will be allocated, in which time data for consecutive patients seen by the participating collaborators will be collected. All requested data can be collected from the routine assessment of the patients that meet the inclusion criteria. Patients will be followed up until the final diagnostic outcome is reached.
Databáze: OpenAIRE