Determinants of SR protein specificity
| Autor: | James L. Manley, Roland Tacke |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Genetics
Messenger RNA Binding Sites Base Sequence Serine-Arginine Splicing Factors RNA Splicing Nuclear Proteins RNA-Binding Proteins Cell Biology Biology Phosphoproteins Family member SR protein RNA splicing RNA Precursors Animals Humans Systematic evolution of ligands by exponential enrichment Protein Binding |
| Zdroj: | Current Opinion in Cell Biology. 11:358-362 |
| ISSN: | 0955-0674 |
| Popis: | The SR (Ser-Arg) proteins are a family of nuclear factors that play multiple important roles in splicing of mRNA precursors in metazoan organisms, functioning in both constitutive and regulated splicing. Certain of these functions are redundant, such that any single SR proteins will suffice, but other functions are unique and are specific to a given family member. A number of studies during the past year have investigated the basis for SR protein specificity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect