Propofol Sedation During Awake Craniotomy for Seizures
| Autor: | Cynthia S. Kubu, Laurie A. Miller, Adrian W. Gelb, Rosemary A. Craen, John P. Girvin, Andrew G. Parrent, Michael Eliasziw, Joyce Kirkby, Ian A. Herrick |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.drug_class Sedation Conscious Sedation Fentanyl Epilepsy Seizures Monitoring Intraoperative medicine Humans Hypnotics and Sedatives Droperidol Prospective Studies Propofol Bupivacaine business.industry Analgesia Patient-Controlled Electroencephalography Nerve Block Middle Aged medicine.disease Dimenhydrinate Surgery Analgesics Opioid Anesthesiology and Pain Medicine Anesthesia Sedative Anticonvulsants Female medicine.symptom business Craniotomy Adjuvants Anesthesia Antipsychotic Agents medicine.drug |
| Zdroj: | Anesthesia & Analgesia. 84:1285-1291 |
| ISSN: | 0003-2999 |
| DOI: | 10.1097/00000539-199706000-00021 |
| Popis: | This prospective study evaluated the safety and efficacy of patient-controlled sedation (PCS) using propofol during awake seizure surgery performed under bupivacaine scalp blocks. Thirty-seven patients were randomized to receive either propofol PCS combined with a basal infusion of propofol (n = 20) or neurolept analgesia using an initial bolus dose of fentanyl and droperidol followed by a fentanyl infusion (n = 17). Both groups received supplemental fentanyl and dimenhydrinate for intraoperative pain and nausea, respectively. Comparisons were made between groups for sedation, memory, and cognitive function, patient satisfaction, and incidence of complications. Levels of intraoperative sedation and patient satisfaction were similar between groups. Memory and cognitive function were well preserved in both groups. The incidence of transient episodes of ventilatory rate depression ( |
| Databáze: | OpenAIRE |
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