Neuraminidase inhibitory terpenes from endophyticCochliobolussp

Autor: Gao-Fei Zhang, Hui Ming Ge, Ren-Xiang Tan, Wei Wang, Zhi-Kai Guo, Jiang Tao Cui
Rok vydání: 2011
Předmět:
Zdroj: Journal of Asian Natural Products Research. 13:761-764
ISSN: 1477-2213
1028-6020
Popis: The chemical study of endophytic fungus of Cochliobolus led to the isolation of 10 terpenes (1-10), including one new compound named isocochlioquinone B (1). Their structures were elucidated on the basis of spectroscopic methods, including 2D NMR techniques. Compounds 5-7 showed significant neuraminidase inhibitory activity with IC(50) values of 0.79-1.75 μM.
Databáze: OpenAIRE
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