Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis: Multicenter Lombardy Registry
| Autor: | Cristina Giannattasio, Riccardo Mantovani, Aurelia Grosu, Giovanni Battista Perego, Paola Sormani, Antonello Gavazzi, Giovanni Peretto, Daniele Briguglia, Marisa Varrenti, Marco Metra, Carlo Campana, Maria Frigerio, Stefania Colombo, Claudia Raineri, Jeness Campodonico, Salvatore I. Caico, Carlo Lombardi, Silvia Guglielmetto, Manlio Cipriani, Daniela Pini, Enrico Ammirati, Fabrizio Oliva, Fabrizio Morandi, Michele Senni, Piergiuseppe Agostoni, Claudio Moro, A. Ciro, Armando Belloni, Laura Scelsi, Valentina Carubelli, Andrea Mortara, Annalisa Turco, Paolo G. Camici, Patrizia Pedrotti, Antonio Mafrici, Cristina Conca, Alberto Maestroni, Giuseppe Di Tano |
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| Přispěvatelé: | Ammirati, E, Cipriani, M, Moro, C, Raineri, C, Pini, D, Sormani, P, Mantovani, R, Varrenti, M, Pedrotti, P, Conca, C, Mafrici, A, Grosu, A, Briguglia, D, Guglielmetto, S, Battista Perego, G, Colombo, S, Caico, S, Giannattasio, C, Maestroni, A, Carubelli, V, Metra, M, Lombardi, C, Campodonico, J, Agostoni, P, Peretto, G, Scelsi, L, Turco, A, Di Tano, G, Campana, C, Belloni, A, Morandi, F, Mortara, A, Cirò, A, Senni, M, Gavazzi, A, Frigerio, M, Oliva, F, Camici, P |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Time Factors Adolescent Biopsy Myocarditi 030204 cardiovascular system & hematology Outcome (game theory) cardiac magnetic resonance Ventricular Function Left 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Physiology (medical) Acute myocarditi medicine Humans 030212 general & internal medicine Hospital Mortality Registries Aged Retrospective Studies business.industry Cardiovascular Agents Stroke Volume MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE Middle Aged Magnetic Resonance Imaging Troponin Hospitalization Myocarditis Acute myocarditis Treatment Outcome Italy Cohort endomyocardial biopsy Acute Disease outcome Heart Transplantation Female Presentation (obstetrics) heart transplantation Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Circulation. 138(11) |
| ISSN: | 1524-4539 |
| Popis: | Background: There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how patients admitted with suspected AM are managed. We report characteristics, in-hospital management, and long-term outcome of patients with AM based on a retrospective multicenter registry from 19 Italian hospitals. Methods: A total of 684 patients with suspected AM and recent onset of symptoms (70 years of age and those >50 years of age without coronary angiography were excluded. The final study population comprised 443 patients (median age, 34 years; 19.4% female) with AM diagnosed by either endomyocardial biopsy or increased troponin plus edema and late gadolinium enhancement at cardiac magnetic resonance. Results: At presentation, 118 patients (26.6%) had left ventricular ejection fraction P P P =0.18). After a median time of 196 days, 200 patients had follow-up cardiac magnetic resonance, and 8 of 55 (14.5%) with complications at presentation had left ventricular ejection fraction Conclusions: In this contemporary study, overall serious adverse events after AM were lower than previously reported. However, patients with left ventricular ejection fraction |
| Databáze: | OpenAIRE |
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