Endoscopic and MRI response evaluation following neoadjuvant treatment for rectal cancer: a pictorial review with matched MRI, endoscopic, and pathologic examples
Autor: | Richard Kim, Julian Sanchez, Seth Felder, Sophie Dessureault, Arthur Parsee, Jessica M. Frakes, James Costello, Iman Imanirad, Sebastian Feuerlein, Sarah E. Hoffe |
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Rok vydání: | 2020 |
Předmět: |
Treatment response
medicine.medical_specialty Colorectal cancer Urology Locally advanced Tumor response 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Neoadjuvant treatment Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Nonoperative management Watchful Waiting Radiological and Ultrasound Technology medicine.diagnostic_test Rectal Neoplasms business.industry Rectum Gastroenterology Hepatology medicine.disease Magnetic Resonance Imaging Neoadjuvant Therapy Endoscopy Treatment Outcome 030220 oncology & carcinogenesis Radiology Neoplasm Recurrence Local business |
Zdroj: | Abdominal Radiology. 46:1783-1804 |
ISSN: | 2366-0058 2366-004X |
DOI: | 10.1007/s00261-020-02827-6 |
Popis: | A nonoperative management strategy, or Watch-and-Wait, following neoadjuvant therapies of locally advanced rectal adenocarcinoma is increasingly considered for select patients. Yet, standardized tumor response assessment to best select and surveil suitable patients remains an unmet clinical challenge. Endoscopic and MRI currently provide the most reliable tumor response estimations. However, resources illustrating variable tumor responses to neoadjuvant therapies remain limited. This pictorial review aims to provide detailed and annotated examples of common endoscopic and MRI findings of rectal cancer treatment response, while also emphasizing their respective diagnostic shortcomings and consequently, the necessity for a multidisciplinary approach to optimally manage these patients. |
Databáze: | OpenAIRE |
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