Synthesis, structural and conformational study of some ureas derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9β-amine
| Autor: | B. Gil-Alberdi, F Iarriccio, Juana Bellanato, Pedro Carmona, Isabel Iriepa, Enrique Gálvez |
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| Přispěvatelé: | Comisión Interministerial de Ciencia y Tecnología, CICYT (España) |
| Rok vydání: | 1999 |
| Předmět: |
Vibrational spectroscopy
Cyclohexane Stereochemistry Organic Chemistry Infrared spectroscopy Nuclear magnetic resonance spectroscopy Carbon-13 NMR 4-diphenyl-3-azabicyclo[3.3.1]nonan-9β-amine Ring (chemistry) Analytical Chemistry Inorganic Chemistry chemistry.chemical_compound NMR spectroscopy chemistry Moiety Amine gas treating Piperidine 3-Methyl-2 4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-amine Spectroscopy 3-Methyl-2 |
| Zdroj: | Digital.CSIC: Repositorio Institucional del CSIC Consejo Superior de Investigaciones Científicas (CSIC) Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 0022-2860 |
| DOI: | 10.1016/s0022-2860(98)00946-6 |
| Popis: | A series of ureas derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9β-amine were synthesized and studied by IR, Raman, 1H and 13C NMR spectroscopy. These compounds adopt in CDCl3 a preferred flattened chair–chair conformation with the cyclohexane ring more flattened than the piperidine moiety, and the N–CH3 groups in equatorial position. IR and 1H and 13C NMR data show the presence of at least two conformations at the urea unity. These results are supported by molecular modelling studies. We thank the Spanish “Comision Interministerial de Ciencia y Tecnologı́a” (Grant SAF 95-0639) for support of this research. |
| Databáze: | OpenAIRE |
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