Comparison of painful and painless left ventricular dysfunction recorded during ambulatory ventricular function monitoring in angina pectoris secondary to coronary artery disease

Autor: Robert C. Leinbach, Herman K. Gold, Junichi Taki, H. William Strauss, Tsunehiro Yasuda, Scott D. Flamm, Adolph M. Hutter
Rok vydání: 1992
Předmět:
Zdroj: The American Journal of Cardiology. 70:1555-1558
ISSN: 0002-9149
DOI: 10.1016/0002-9149(92)90456-9
Popis: Left ventricular (LV) function and the electrocardiogram of 55 patients with coronary artery disease and angina were monitored for a mean of 3.2 +/- 1.9 hours with an ambulatory LV function monitor. During the monitoring interval, patients performed daily activities such as sitting, walking, climbing stairs, and eating. Sixty episodes of transient reduction in ejection fraction of5% lasting60 seconds were observed in 24 patients; 13 episodes were associated with typical angina, but 47 were asymptomatic. Asymptomatic episodes had a shorter duration of ventricular dysfunction (116 +/- 49 vs 189 +/- 113 seconds; p0.05), and smaller increases in relative end-diastolic and end-systolic volumes (end-diastolic 0.9 +/- 5.4% vs 4.6 +/- 4.9% [p0.05], and end-systolic 21 +/- 11% vs 35 +/- 20% [p0.05]) than did symptomatic ones. When a subset of patients with both symptomatic and asymptomatic episodes were analyzed, similar results were observed: in asymptomatic episodes, duration was shorter (82 +/- 31 vs 200 +/- 110 seconds; p0.005), ejection fraction decrease was smaller (-7.3 +/- 2.6% vs -11.0 +/- 4.7%; p0.05), and end-systolic volume increase was smaller (23 +/- 12% vs 37 +/- 19%; p0.05). The data suggest that asymptomatic transient LV dysfunction is less severe and of shorter duration in patients with angina pectoris.
Databáze: OpenAIRE