Dual‐target affinity analysis and separation of α ‐amylase and α ‐glucosidase inhibitors from Morus alba leaves using a magnetic bifunctional immobilized enzyme system

Autor:	Shuang Guo, Shuo Liu, Jing Meng, Dongyu Gu, Yi Wang, Dajun He, Yi Yang
Rok vydání:	2022
Předmět:	Pharmacology Clinical Biochemistry Drug Discovery General Medicine Molecular Biology Biochemistry Analytical Chemistry
Zdroj:	Biomedical Chromatography. 37
ISSN:	1099-0801 0269-3879
DOI:	10.1002/bmc.5571
Popis:	Morus alba leaves are a natural product with great antidiabetic potential. However, the therapeutic efficacy of natural products is usually achieved through the interaction of active compounds with specific targets. Among them, active compounds with multi-target therapeutic functions are more effective than single-target enzymes. In this study, a bienzyme system was constructed by co-immobilizing α-amylase and α-glucosidase onto Fe
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf36fadf9f7d75217fd90f51d3603a8 https://doi.org/10.1002/bmc.5571 Zobrazit plný text záznamu Plný text