Tricyclic plasma levels in depressed outpatients treated with amitriptyline
| Autor: | Karl Rickels, George D. Case, Howard Benjamin Hucker, Charles C. Weise |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Amitriptyline Tricyclic antidepressant Nortriptyline Gastroenterology chemistry.chemical_compound Caffeine Internal medicine Coffee intake medicine Humans Pharmacology chemistry.chemical_classification Depression Smoking Plasma levels chemistry Anesthesia Female Psychology Tricyclic medicine.drug Psychopathology |
| Zdroj: | Psychopharmacology. 80:14-18 |
| ISSN: | 1432-2072 0033-3158 |
| DOI: | 10.1007/bf00427486 |
| Popis: | Seventy-four patients were treated with 150 mg/day amitriptyline (AT) to determine possible correlations between clinical improvement, demographic variables, and AT and nortriptyline (NT) plasma levels. Plasma level determinations after 2 and 6 weeks of treatment revealed that moderately significant correlations existed between AT plasma levels and clinical improvement, dosage intake, age, weight, sex, and coffee intake. Some of these findings were more pronounced after 2, and some after 6 weeks of treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink