Gold core-satellite nanostructure linked by oligonucleotides for detection of glutathione with LSPR scattering spectrum

Autor: Ting-Ting Zhai, Ying-Bo Liu, Yue-Bo Wang, Yan-Yan Liang, Xing-Hua Xia
Rok vydání: 2019
Předmět:
Zdroj: Talanta. 193:123-127
ISSN: 0039-9140
DOI: 10.1016/j.talanta.2018.09.096
Popis: We demonstrated a sensitive method for detection of glutathione (GSH) based on LSPR scattering spectrum using gold core-satellite nanostructure linked by T-Hg2+-T base pair. The core-satellite assembly caused coupling between plasmonic nanoparticles, which inducing distinct change of LSPR peak wavelength. As the interaction between Hg2+ and GSH, the core-satellite nanostructure would be disassembled, which accompanied with spectral blue-shift of the scattering spectrum. By using this method, GSH could be quantitatively detected, and the detection limits can reach to 0.1 µM.
Databáze: OpenAIRE