Influence of Natural Lung Surfactant Inhalations on Clinical Symptoms and Pulmonary Function Parameters in Patients with Bronchial Asthma. Communication 1
| Autor: | A. Kochneva, E. Akulova, V. Volchkov, O. Stepanova, A. Shulga, O. Rosenberg, A. Seiliev, S. Lukyanov, O. Lovacheva, K. Shapovalov |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
lung surfactant
medicine.medical_specialty lcsh:Medicine 02 engineering and technology 030226 pharmacology & pharmacy Gastroenterology General Biochemistry Genetics and Molecular Biology Pulmonary function testing 03 medical and health sciences 0302 clinical medicine Pulmonary surfactant Internal medicine medicine In patient Asthma General Immunology and Microbiology business.industry General Neuroscience pulmonary function lcsh:R dose respiratory system 021001 nanoscience & nanotechnology medicine.disease respiratory tract diseases bronchial asthma inhaled corticosteroids 0210 nano-technology business |
| Zdroj: | International Journal of Biomedicine, Vol 6, Iss 4, Pp 255-258 (2016) |
| ISSN: | 2158-0529 2158-0510 |
| Popis: | Background: Damage to lung surfactant (LS) enabling the lung local immunity may contribute to the development of bronchial inflammation in patients with bronchial asthma. Methods and Results: A 40-day course of 16 LS (Surfactant-BL) inhalations at the dose of 25mg was added to inhaled corticosteroids (ICS) and short/long-acting bronchodilators or combined inhalers in 14 patients with bronchial asthma. After 7 inhalations, patients demonstrated a significant decrease in shortness of breath and bronchospasm attacks, double reduction of ICS dose (p=0.01), and improvement of pulmonary function. Forced vital capacity (FVC) increases during treatment in a linear fashion (y=62.9+5.60•x; p |
| Databáze: | OpenAIRE |
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