The complex admixture history and recent southern origins of Siberian populations
| Autor: | Rostislav Matveev, Vladimir L. Osakovsky, Brigitte Pakendorf, Innokentiy Novgorodov, Irina Pugach, V. A. Spitsyn, Sergey N. Makarov, Mark Stoneking |
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| Přispěvatelé: | Department of Evolutionary Genetics, Max-Planck-Institut, Dynamique Du Langage (DDL), Université Lumière - Lyon 2 (UL2)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology Population Replacement 030105 genetics & heredity Gene flow 0601 history and archaeology admixture dating Phylogeny 0303 health sciences education.field_of_study 060102 archaeology Last Glacial Maximum 06 humanities and the arts Genomics Biological Evolution LGM Phylogeography Geography multiple admixture events Cold period Gene Flow Pastoralism Population Genetic admixture Biology Polymorphism Single Nucleotide wavelets Evolution Molecular Prehistory 03 medical and health sciences back migration Asian People Genetic variation Genetics Humans education Domestication Molecular Biology Discoveries Ecology Evolution Behavior and Systematics 030304 developmental biology Genetic Variation 15. Life on land Siberia Genetics Population 030104 developmental biology Haplotypes Evolutionary biology population replacement |
| Zdroj: | Molecular Biology and Evolution Molecular Biology and Evolution, Oxford University Press (OUP), 2016, 33 (7), pp.1777-1795. ⟨10.1093/molbev/msw055⟩ |
| ISSN: | 0737-4038 1537-1719 |
| Popis: | Although Siberia was inhabited by modern humans at an early stage, there is still debate over whether this area remained habitable during the extremely cold period of the Last Glacial Maximum or whether it was subsequently repopulated by peoples with a recent shared ancestry. Previous studies of the genetic history of Siberian populations were hampered by the extensive admixture that appears to have taken place among these populations, since commonly used methods assume a tree-like population history and at most single admixture events. We therefore developed a new method based on the covariance of ancestry components, which we validated with simulated data, in order to investigate this potentially complex admixture history and to distinguish the effects of shared ancestry from prehistoric migrations and contact. We furthermore adapted a previously devised method of admixture dating for use with multiple events of gene flow, and applied these methods to whole-genome genotype data from over 500 individuals belonging to 20 different Siberian ethnolinguistic groups. The results of these analyses indicate that there have indeed been multiple layers of admixture detectable in most of the Siberian populations, with considerable differences in the admixture histories of individual populations, and with the earliest events dated to not more than 4500 years ago. Furthermore, most of the populations of Siberia included here, even those settled far to the north, can be shown to have a southern origin. These results provide support for a recent population replacement in this region, with the northward expansions of different populations possibly being driven partly by the advent of pastoralism, especially reindeer domestication. These newly developed methods to analyse multiple admixture events should aid in the investigation of similarly complex population histories elsewhere. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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