High dose intravenous gammaglobulin and platelet transfusions in leukaemic HLA-immunized patients
| Autor: | N. Duedari, P. Bierling, Catherine Cordonnier, Jean-Paul Vernant, M. Rodet, A. Pesce, Henri Rochant |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Blood Platelets Male Cell Survival Dose-Response Relationship Immunologic Platelet Transfusion Human leukocyte antigen Refractory HLA Antigens Isoantibodies Pregnancy hemic and lymphatic diseases Humans Medicine Blood Transfusion Hla antibodies Platelet Platelet recovery business.industry Intravenous gammaglobulin Gamma globulin Hematology Acute leukaemias Leukemia Myeloid Acute Injections Intravenous Immunology Female Immunization gamma-Globulins business |
| Zdroj: | Scandinavian Journal of Haematology. 33:215-220 |
| ISSN: | 0036-553X |
| DOI: | 10.1111/j.1600-0609.1984.tb02399.x |
| Popis: | 3 aplastic patients with acute leukaemia, strongly HLA-immunized and refractory to platelet transfusions, received polyvalent gammaglobulin i.v. infusions (0.4 g/kg/d for 5 or 6 d) in association with daily random platelet transfusions. Platelet recovery was obtained in 2 patients. The 3rd patient did not show any significant rise in platelet count. The ability of gammaglobulin to prolong the life-span of incompatible transfused platelets could facilitate the management of HLA-immunized patients. |
| Databáze: | OpenAIRE |
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