Distribution of neurotensin-containing fibers in the frontal cortex of the macaque monkey
| Autor: | Hiroko Matsumura, Keiji Satoh |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Tyrosine 3-Monooxygenase Neuropeptide Substance P Biology Nucleus accumbens Immunoenzyme Techniques chemistry.chemical_compound Nerve Fibers medicine Animals Fiber Neurotensin Anterior cingulate cortex Cerebral Cortex Catecholaminergic General Neuroscience digestive oral and skin physiology Anatomy medicine.anatomical_structure nervous system chemistry Organ Specificity Cerebral cortex Macaca Somatostatin hormones hormone substitutes and hormone antagonists |
| Zdroj: | The Journal of Comparative Neurology. 298:215-223 |
| ISSN: | 1096-9861 0021-9967 |
| DOI: | 10.1002/cne.902980206 |
| Popis: | The distribution of neurotensin-containing fibers was examined in the frontal cortex of the monkey Macaca fuscata using the immunoperoxidase histochemical technique. An extremely dense network of neurotensin-containing fibers was observed in the medial prefrontal regions. The majority of cortical neurotensin fibers was observed in the anterior cingulate cortex (Walker's area 24) and adjacent medial prefrontal regions (areas 6 and 32). In area 24, the fiber density was similar to that in the nucleus accumbens. Immunoreactive fibers were particularly dense in two pyramidal layers (III, V). The medial prefrontal regions, areas 6 and 32, contained a moderate density of immunoreactive fibers. This regional distribution of neurotensin-containing fibers was not observed in other cortical fiber systems that contained substance P, somatostatin, or tyrosine hydroxylase. No neurotensin-containing cell bodies were observed in the frontal cortex. The present study demonstrates that the laminar and regional distributions of neurotensin-containing fibers are unique when compared to those of substance P- or somatostatin-containing fibers, and also distinct from that of catecholaminergic fibers. The distribution of telencephalic neurotensin fibers points to a relationship with limbic structures. |
| Databáze: | OpenAIRE |
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