Value of contrast-enhanced malignancy imaging features in secondary grade diagnosis of BI-RADS-US type 4 breast lesions
| Autor: | Han Wei, Di Li Mu La Ti Ai Si Mu Tu La, Hou Xueqin, Tao Song, Zhi Ming Li, Gao Junxi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Breast imaging media_common.quotation_subject Contrast Media Breast Neoplasms BI-RADS Malignancy 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences 0302 clinical medicine Humans Medicine Contrast (vision) Aged Retrospective Studies media_common business.industry General Medicine Middle Aged Image Enhancement medicine.disease Oncology 030220 oncology & carcinogenesis Female Ultrasonography Mammary Radiology Ultrasonography business Value (mathematics) |
| Zdroj: | Tumori Journal. 107:424-431 |
| ISSN: | 2038-2529 0300-8916 |
| Popis: | Purpose: To explore the value of contrast-enhanced malignancy imaging features in secondary grade diagnosis of Breast Imaging Reporting and Data System for Ultrasonography (BI-RADS-US) type 4 breast lesions. Methods: After initial diagnosis by ultrasound, 124 BI-RADS-US type 4 patients with 130 lesions were examined by contrast-enhanced ultrasound (CEUS) and were classified again before surgery according to five contrast-enhanced malignancy imaging features: inhomogeneous enhancement, peripheral ring-like enhancement, expansive enhancement, internal filling defects, and surrounding radioactive convergence. Lesions with no contrast-enhanced features of malignancy were categorized as type 3; lesions with one, two, or three features of malignancy were categorized as type 4A, 4B, or 4C, respectively; and lesions with four or more indices of malignancy were categorized as type 5. The value of contrasted imaging features of malignancy in diagnosing BI-RADS-US type 4 breast lesions was analyzed. Results: The accuracy of CEUS diagnosis for type 3 lesions was 93.8% (46/49), 76.9% (10/13) for type 4A, 71.4% (5/7) for type 4B, 75.0% (9/12) for type 4C, and 93.8% (46/49) for type 5 lesions. The sensitivity of CEUS in diagnosing malignant lesions was 90.4%, specificity was 83.6%, and accuracy was 86.9%. CEUS decreased the benign lesion biopsy ratio to 68.5% (46/67) and increased the diagnosis ratio of malignant lesions to 73.0% (46/63). Conclusions: CEUS can further optimize the classification of BI-RADS-US type 4 breast lesions and may provide a better reference basis for clinical diagnosis and treatment of those breast lesions. |
| Databáze: | OpenAIRE |
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