Evaluation of an MR-only interstitial gynecologic brachytherapy workflow using MR-line marker for catheter reconstruction
| Autor: | Moti Paudel, Eric Leung, Mackenzie Smith, Frances Tonolete, Alexandru Nicolae, Amani Shaaer, Ananth Ravi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Organs at Risk Catheters Vaginal Neoplasms medicine.medical_treatment Brachytherapy Urinary Bladder Planning target volume Uterine Cervical Neoplasms 030218 nuclear medicine & medical imaging Workflow 03 medical and health sciences 0302 clinical medicine Colon Sigmoid Image Processing Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging Radiometry Gynecologic brachytherapy Aged Contouring medicine.diagnostic_test business.industry Radiotherapy Planning Computer-Assisted Interstitial brachytherapy Rectum Magnetic resonance imaging Radiotherapy Dosage Middle Aged Magnetic Resonance Imaging Endometrial Neoplasms Catheter Oncology 030220 oncology & carcinogenesis Female business Nuclear medicine |
| Zdroj: | Brachytherapy. 19(5) |
| ISSN: | 1873-1449 |
| Popis: | Magnetic resonance imaging (MRI) offers excellent soft-tissue contrast enabling the contouring of targets and organs at risk (OARs) during gynecological interstitial brachytherapy procedure. Despite its benefit, one of the main challenges toward MRI-only workflows is that the implanted catheters are not reliably visualized on MR images. This study aims to evaluate the feasibility of MR-only workflow using an in-house MR line marker during interstitial gynecological high-dose-rate (HDR) brachytherapy.Ten patients diagnosed with locally advanced cervical cancer treated with HDR brachytherapy were included in this study. The hybrid CT/MR-treated plan was used as the study reference plan. Five users manually reconstructed the catheter's path on MR images (3D T1- and T2-weighted). Subsequently, the dwell positions from the users' plans were superimposed on the reference plans to evaluate the dosimetric impact of the using MR-only for catheter reconstruction in comparison with hybrid CT/MR approach. Variability of dwell positions between users and reconstruction time was also evaluated.More than 96.90% of catheter reconstruction variations were2 mm. No statistical differences were reported between MR-only and hybrid CT/MR in gross tumor volume DThe feasibility of MR-only workflow using MR line marker during interstitial gynecological HDR brachytherapy has been validated in this study. The results show that the MR-only workflow is equivalent to the conventional hybrid CT/MR approach in terms of gross tumor volume and high-risk clinical target volume coverage and respecting of OARs dose limits. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|