Combined ultrasound and serologic screening for hepatic alveolar echinococcosis in central China
Autor: | Yunhai Wang, Philip S. Craig, Patrick Giraudoux, Gitte Bartholomot, Calum N. L. Macpherson, Da Zhong Shi, S Harraga, Guy Barnish, Dominique A. Vuitton |
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Přispěvatelé: | WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Xinjiang Medical University, Chinese Government, Biomedical Sciences Research Institute, University of Salford, Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ) |
Rok vydání: | 2002 |
Předmět: |
Male
Pathology MESH : Aged MESH: Echinococcus Serology 0302 clinical medicine MESH : Child Seroepidemiologic Studies MESH: Child Surveys and Questionnaires MESH : Seroepidemiologic Studies MESH : Echinococcus MESH : Female MESH: Animals Child Ultrasonography MESH: Aged 0303 health sciences MESH: Middle Aged biology Ultrasound MESH: Echinococcosis Hepatic MESH : Questionnaires MESH: Enzyme-Linked Immunosorbent Assay MESH : Adult Middle Aged MESH : Enzyme-Linked Immunosorbent Assay Echinococcosis MESH: China 3. Good health Infectious Diseases Female medicine.symptom Adult [ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology China Echinococcosis Hepatic medicine.medical_specialty Adolescent MESH : Male 030231 tropical medicine Antibodies Helminth Helminthiasis Enzyme-Linked Immunosorbent Assay Echinococcus multilocularis Malignancy Lesion 03 medical and health sciences MESH: Antibodies Helminth MESH : Adolescent Virology medicine MESH : China Animals Humans MESH : Middle Aged [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology MESH : Antibodies Helminth Aged MESH: Adolescent MESH: Humans MESH: Seroepidemiologic Studies 030306 microbiology business.industry MESH: Questionnaires MESH : Humans MESH: Adult biology.organism_classification medicine.disease MESH: Male Echinococcus Parasitology MESH : Animals MESH : Echinococcosis Hepatic business MESH: Female |
Zdroj: | American Journal of Tropical Medicine and Hygiene American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2002, 66 (1), pp.23-9 The American journal of tropical medicine and hygiene The American journal of tropical medicine and hygiene, 2002, 66 (1), pp.23-9 |
ISSN: | 1476-1645 0002-9637 |
Popis: | International audience; Alveolar echinococcosis (AE), caused by Echinococcus multilocularis, is a zoonotic helminthic disease that can mimic malignancy. In the 1970s, foci of the disease were found in central China. The aim of the present study was to estimate the prevalence of AE in humans in 2 districts of south Gansu Province, China, by use of ultrasound and Echinococcus serology. After answering an epidemiological questionnaire, 2,482 volunteers from 28 villages underwent ultrasound. Serology via enzyme-linked immunosorbent assay for antibody activity was performed on whole blood collected on filter paper in all subjects; on serum from subjects with an abnormal ultrasound image; and on randomly chosen subjects that either had no lesions or had atypical lesions. At least one (25.3%) abnormal ultrasound image was observed in 630 of the subjects screened. A typical lesion of progressive AE was found in 84 subjects (3.4%). Serologies were positive in 77 (96%) of 80 of patients who had lesions typical of progressive AE. Ultrasound is useful for screening for AE in endemic regions. |
Databáze: | OpenAIRE |
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