Combined ultrasound and serologic screening for hepatic alveolar echinococcosis in central China

Autor: Yunhai Wang, Philip S. Craig, Patrick Giraudoux, Gitte Bartholomot, Calum N. L. Macpherson, Da Zhong Shi, S Harraga, Guy Barnish, Dominique A. Vuitton
Přispěvatelé: WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Xinjiang Medical University, Chinese Government, Biomedical Sciences Research Institute, University of Salford, Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC )
Rok vydání: 2002
Předmět:
Male
Pathology
MESH : Aged
MESH: Echinococcus
Serology
0302 clinical medicine
MESH : Child
Seroepidemiologic Studies
MESH: Child
Surveys and Questionnaires
MESH : Seroepidemiologic Studies
MESH : Echinococcus
MESH : Female
MESH: Animals
Child
Ultrasonography
MESH: Aged
0303 health sciences
MESH: Middle Aged
biology
Ultrasound
MESH: Echinococcosis
Hepatic
MESH : Questionnaires
MESH: Enzyme-Linked Immunosorbent Assay
MESH : Adult
Middle Aged
MESH : Enzyme-Linked Immunosorbent Assay
Echinococcosis
MESH: China
3. Good health
Infectious Diseases
Female
medicine.symptom
Adult
[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
China
Echinococcosis
Hepatic
medicine.medical_specialty
Adolescent
MESH : Male
030231 tropical medicine
Antibodies
Helminth
Helminthiasis
Enzyme-Linked Immunosorbent Assay
Echinococcus multilocularis
Malignancy
Lesion
03 medical and health sciences
MESH: Antibodies
Helminth
MESH : Adolescent
Virology
medicine
MESH : China
Animals
Humans
MESH : Middle Aged
[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
MESH : Antibodies
Helminth
Aged
MESH: Adolescent
MESH: Humans
MESH: Seroepidemiologic Studies
030306 microbiology
business.industry
MESH: Questionnaires
MESH : Humans
MESH: Adult
biology.organism_classification
medicine.disease
MESH: Male
Echinococcus
Parasitology
MESH : Animals
MESH : Echinococcosis
Hepatic
business
MESH: Female
Zdroj: American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2002, 66 (1), pp.23-9
The American journal of tropical medicine and hygiene
The American journal of tropical medicine and hygiene, 2002, 66 (1), pp.23-9
ISSN: 1476-1645
0002-9637
Popis: International audience; Alveolar echinococcosis (AE), caused by Echinococcus multilocularis, is a zoonotic helminthic disease that can mimic malignancy. In the 1970s, foci of the disease were found in central China. The aim of the present study was to estimate the prevalence of AE in humans in 2 districts of south Gansu Province, China, by use of ultrasound and Echinococcus serology. After answering an epidemiological questionnaire, 2,482 volunteers from 28 villages underwent ultrasound. Serology via enzyme-linked immunosorbent assay for antibody activity was performed on whole blood collected on filter paper in all subjects; on serum from subjects with an abnormal ultrasound image; and on randomly chosen subjects that either had no lesions or had atypical lesions. At least one (25.3%) abnormal ultrasound image was observed in 630 of the subjects screened. A typical lesion of progressive AE was found in 84 subjects (3.4%). Serologies were positive in 77 (96%) of 80 of patients who had lesions typical of progressive AE. Ultrasound is useful for screening for AE in endemic regions.
Databáze: OpenAIRE
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