Nonarteritic anterior ischaemic optic neuropathy
| Autor: | Sushma Dhar-Munshi, Shu Fen Ho |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Retinal Ganglion Cells
medicine.medical_specialty genetic structures Phosphodiesterase Inhibitors medicine.medical_treatment Optic Disk Scanning laser polarimetry Cataract Extraction Diagnostic Techniques Ophthalmological Optic neuropathy chemistry.chemical_compound Nerve Fibers Optical coherence tomography Anterior ischaemic optic neuropathy Ophthalmology Optic Nerve Diseases medicine Animals Humans Optic Neuropathy Ischemic Arteritis medicine.diagnostic_test business.industry Retinal General Medicine Phosphodiesterase 5 Inhibitors Cataract surgery medicine.disease eye diseases Visual field Disease Models Animal chemistry Optic nerve sense organs business |
| Zdroj: | Current Opinion in Ophthalmology. 19:461-467 |
| ISSN: | 1040-8738 |
| DOI: | 10.1097/icu.0b013e3283112bc8 |
| Popis: | Purpose of review There have been many reports in recent literature concerning the use of scanning laser polarimetry, Heidelberg retinal tomography and optical coherence topography in assessing the optic nerve and peripapillary nerve fibre layer. It is important to assess the validity of new equipment and see whether this has improved our understanding of the disease. There are also reports about possible association of nonarteritic anterior ischaemic optic neuropathy with cataract surgery and phosphodiesterase type-5 inhibitors. This review attempts to look at some of the techniques used and possible associations with nonarteritic anterior ischaemic optic neuropathy. Recent findings Scanning laser polarimetry, Heidelberg retinal tomography and optical coherence tomography have been helpful in quantifying optic nerve and peripapillary retinal nerve fibre layer defects, with different efficacy and limitations. Although these confirm the damage to retinal nerve fibre layer beyond what is detected by standard visual field examination, the effect of cataract surgery and phosphodiesterase type-5 inhibitors remains to be further studied on a larger scale. The few experimental treatments for nonarteritic anterior ischaemic optic neuropathy also need further confirmatory studies. Summary More studies are required to evaluate the benefits of new imaging methods. The availability of a primate model may provide clues to assessing experimental treatments for nonarteritic anterior ischaemic optic neuropathy. |
| Databáze: | OpenAIRE |
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