Preparation and optimization of nilotinib self-micro-emulsifying drug delivery systems to enhance oral bioavailability

Autor:	Ashok Zakkula, Ravi Kumar Jairam, Bhavesh Babulal Gabani, Vinay Kiran, Ramesh Mullangi, Umesh Todmal
Rok vydání:	2020
Předmět:	Drug Male genetic structures media_common.quotation_subject Chemistry Pharmaceutical Pharmaceutical Science Administration Oral Biological Availability Antineoplastic Agents 02 engineering and technology Pharmacology 030226 pharmacology & pharmacy Excipients Rats Sprague-Dawley 03 medical and health sciences Surface-Active Agents 0302 clinical medicine Drug Delivery Systems Drug Discovery medicine Animals Particle Size media_common business.industry Organic Chemistry 021001 nanoscience & nanotechnology Bioavailability Rats Drug Liberation Pyrimidines Nilotinib Solubility Drug delivery Emulsions 0210 nano-technology business medicine.drug
Zdroj:	Drug development and industrial pharmacy. 46(3)
ISSN:	1520-5762
Popis:	Objective: The objective of the current research was to prepare self-micro-emulsifying drug delivery systems (SMEDDS) for BCS class II drug, nilotinib to enhance its oral bioavailability.Methodolog...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cccc24cc03fb9545ced942c382e9ab81 https://pubmed.ncbi.nlm.nih.gov/32067499 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.