Revision Bronchoscopy After Endobronchial Valve Treatment for Emphysema
| Autor: | Sharyn A Roodenburg, Marlies van Dijk, Dirk-Jan Slebos, Karin Klooster, T. David Koster, Jorine E. Hartman |
|---|---|
| Přispěvatelé: | Groningen Research Institute for Asthma and COPD (GRIAC) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
bronchoscopy medicine.medical_treatment International Journal of Chronic Obstructive Pulmonary Disease one-way valve Bronchoscopies Pulmonary function testing 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Valve replacement Bronchoscopy lung volume reduction medicine Effective treatment COPD Humans 030212 general & internal medicine Pneumonectomy Original Research Emphysema medicine.diagnostic_test business.industry Granulation tissue Endobronchial valve General Medicine medicine.disease Surgery medicine.anatomical_structure Treatment Outcome 030228 respiratory system Pulmonary Emphysema business |
| Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease International Journal of Chronic Obstructive Pulmonary Disease, 16, 1127-1136. DOVE MEDICAL PRESS LTD |
| ISSN: | 1176-9106 |
| Popis: | Sharyn A Roodenburg,1,2 Karin Klooster,1,2 Jorine E Hartman,1,2 T David Koster,1,2 Marlies van Dijk,1,2 Dirk-Jan Slebos1,2 1Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; 2Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The NetherlandsCorrespondence: Sharyn A RoodenburgDepartment of Pulmonary Diseases, AA11, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713, GZ, The NetherlandsTel +31 50 361 9194Fax +31 050 3619320Email s.a.roodenburg@umcg.nlBackground: Endobronchial valve (EBV) treatment is an effective treatment for patients with severe emphysema. Revision bronchoscopies after endobronchial valve treatment can be essential to prolong the effect of treatment or address long-term complications.Purpose: To evaluate the indications, endoscopic findings and outcomes of revision bronchoscopies and investigate if any predictors for granulation tissue formation, after EBV treatment, can be identified.Patients and Methods: Patients who underwent EBV treatment between 2016 and 2019 in our hospital, as routine care, were included. If a patient underwent a revision bronchoscopy, data regarding revision bronchoscopies, including indication, finding, intervention and pulmonary function testing (PFT) after revision bronchoscopy were analysed.Results: One hundred seventy-nine patients were included of which 41% required at least one revision bronchoscopy. In 43% of the revision bronchoscopy patients, the indication was loss of initial treatment effect. In 53% of the revision bronchoscopy patients, granulation tissue was found to be the underlying cause. Valve replacement(s) were performed in 51% of the revision bronchoscopy cases. Permanent valve removal was required in 13% of all patients. Overall, revision bronchoscopies led to improvements in PFT outcomes for patients experiencing no or a loss of initial treatment effect. No clinically relevant predictors for granulation tissue formation were identified.Conclusion: Performing a revision bronchoscopy after EBV treatment is a useful procedure leading to an improved treatment effect in most patients. Granulation tissue formation, causing valve dysfunction, is the most common cause of longer term problems.Keywords: bronchoscopy, lung volume reduction, one-way valve, COPD |
| Databáze: | OpenAIRE |
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