Age-associated changes in regional aortic pulse wave velocity
| Autor: | Diane A Vido, Douglas Coast, Christopher M. Kramer, Yong-Lin Hu, Nathaniel Reichek, Reed E. Pyeritz, Walter J. Rogers |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Applanation tonometry Aging medicine.medical_specialty Transducers Hemodynamics Femoral artery medicine.artery Internal medicine Image Processing Computer-Assisted Humans Medicine cardiovascular diseases Pulse wave velocity Aorta Aged medicine.diagnostic_test business.industry Pulse (signal processing) Magnetic resonance imaging Anatomy Middle Aged Magnetic Resonance Imaging Vascular tone cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business Blood Flow Velocity circulatory and respiratory physiology |
| Zdroj: | Journal of the American College of Cardiology. 38:1123-1129 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/s0735-1097(01)01504-2 |
| Popis: | OBJECTIVESThis study was designed to determine noninvasively the age-associated changes in regional mechanical properties in normals using phase-contrast magnetic resonance imaging (PCMRI).BACKGROUNDIt has been well documented that there is a progressive increase in aortic pulse wave velocity (PWV) with age. Previously, PWV has been measured at a single aortic location, or has compared arterial waves between carotid and femoral points to determine PWV.METHODSApplanation tonometry (TONO) and in-plane PCMR was performed in 24 volunteers (12 men) ranging in age from 21 to 72 years old. The PCMRI PWV was measured in three aortic segments. As validation, TONO was performed to determine PWV between the carotid and femoral artery.RESULTSWhen PCMRI PWV was averaged over the three locations, it was not different from TONO (7.9 ± 2.3 vs. 7.6 ± 2.4 m/s, respectively). When the volunteers were divided into groups of |
| Databáze: | OpenAIRE |
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