Giant Transposons in Eukaryotes: Is Bigger Better?
| Autor: | Arkhipova, Irina R, Yushenova, Irina A |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Transposable element Retroelements transposase ved/biology.organism_classification_rank.species Rotifera Retrotransposon Invited Rev Biology 010603 evolutionary biology 01 natural sciences Genome 03 medical and health sciences reverse transcriptase transposition Genetics Recombinase Animals Model organism Ecology Evolution Behavior and Systematics Transposase 030304 developmental biology 0303 health sciences ved/biology Eukaryota food and beverages Planarians Telomere Interaction with host Evolutionary biology DNA Transposable Elements Identification (biology) mobile DNA transposable elements |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| DOI: | 10.1093/gbe/evz041 |
| Popis: | Transposable elements (TEs) are ubiquitous in both prokaryotes and eukaryotes, and the dynamic character of their interaction with host genomes brings about numerous evolutionary innovations and shapes genome structure and function in a multitude of ways. In traditional classification systems, TEs are often being depicted in simplistic ways, based primarily on the key enzymes required for transposition, such as transposases/recombinases and reverse transcriptases. Recent progress in whole-genome sequencing and long-read assembly, combined with expansion of the familiar range of model organisms, resulted in identification of unprecedentedly long transposable units spanning dozens or even hundreds of kilobases, initially in prokaryotic and more recently in eukaryotic systems. Here, we focus on such oversized eukaryotic TEs, including retrotransposons and DNA transposons, outline their complex and often combinatorial nature and closely intertwined relationship with viruses, and discuss their potential for participating in transfer of long stretches of DNA in eukaryotes. |
| Databáze: | OpenAIRE |
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