Characteristics and outcome of patients with solid tumour requiring admission to the intensive care unit. Usefulness of three severity score systems
| Autor: | Constanza Maximiano Alonso, José Ferreres Franco, Alfonso Ortega López, Héctor Villanueva Fernández, Marina Pérez Redondo, Diego Palacios Castañeda, Bárbara Balandín Moreno, Miguel Valdivia de la Fuente, María Lucía Pérez Pérez, Sara Alcántara Carmona, Ana Royuela Vicente, Javier García Sanz, Ana Gonzaga López |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Demographics Organ Dysfunction Scores Hospital mortality Severity of Illness Index law.invention Acute illness 03 medical and health sciences 0302 clinical medicine Patient Admission law Neoplasms Illness severity Medicine Humans 030212 general & internal medicine Hospital Mortality APACHE Aged Retrospective Studies Solid tumour APACHE II business.industry Significant difference General Medicine Length of Stay Middle Aged Intensive care unit Life Support Care Intensive Care Units Logistic Models ROC Curve Emergency medicine Female business |
| Zdroj: | Medicina clinica. 153(7) |
| ISSN: | 1578-8989 |
| Popis: | To describe the characteristics and the evolution of patients with solid tumours admitted to the ICU and to identify factors associated with hospital mortality and to evaluate three illness severity scores.Descriptive study including 132 patients with solid tumour admitted to the ICU (2010-2016). Demographics and cancer-related data, organ failures, life-supporting therapies and severity scores: APACHE II, SOFA and ICU Cancer Mortality Model (ICMM) were collected.There were 58 patients admitted for medical reasons and 74 for scheduled surgery. The ICU and hospital mortality rate were 12.9% and 19.7%, respectively. The medical reason for admission, the number of organ failures, and the need of life-supporting therapies were significantly associated with a higher mortality (p0.05). In the logistic regression analysis, the three severity scores: SOFA (OR 1.18, 95% IC 1.14-1.48), APACHE II (OR 1.11, 95% CI 1.09-1.27), and ICMM (OR 1.03, 95% CI 1.02-1.07) were independently associated with a higher mortality (p0.05). To evaluate the discrimination, the area under the receiver operating characteristics curves (AUROC) were calculated: APACHE II (0.795, 95% CI 0.69-0.9), SOFA (0.77, 95% CI 0.69-0.864) and ICMM (0.794, 95% CI 0.697-0.891). The comparison of AUC ROC after DeLong's test showed no difference between them.Hospital mortality was associated with the type and severity of acute illness. The three severity scores were useful to assess outcome and accurate in the discrimination, but we did not find a significant difference between them. |
| Databáze: | OpenAIRE |
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