Lung function measurement in prematurely born preschool children with and without chronic lung disease
| Autor: | P. Bridge, V. Kairamkonda, N V Subhedar, J Richardson, Nigel J Shaw |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Birth weight Pulmonary function testing Humans Medicine Bronchopulmonary Dysplasia business.industry Infant Newborn Case-control study Obstetrics and Gynecology Gestational age medicine.disease Interrupter Technique Respiratory Function Tests Bronchopulmonary dysplasia Premature birth Case-Control Studies Child Preschool Pediatrics Perinatology and Child Health Ambulatory Feasibility Studies Premature Birth Female business |
| Zdroj: | Journal of Perinatology. 28:199-204 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/sj.jp.7211911 |
| Popis: | Prematurely born infants often have recurrent wheeze and long-term respiratory morbidity at follow-up. Assessment of airways obstruction in preschool children is feasible using the interrupter resistance (Rint) but has rarely been examined in preterm children with and without chronic lung disease (CLD). The objective of this study was to determine lung function measured by the interrupter technique, its feasibility in the ambulatory setting and respiratory health in prematurely born preschool children with and without CLD. Preterm children of 2 to 4 years with severe CLD (>30% oxygen at 36 weeks and discharged home receiving supplemental oxygen) (n=43, median gestational age 27 weeks and median birth weight 995 g) and without CLD (n=33, median gestational age 29 weeks and median birth weight 1366 g) attempting lung function test for the first time were enrolled. Respiratory symptoms score was calculated using a questionnaire. A single set of 10 consecutive Rint measurements was obtained using a portable device (MicroRint). Median of at least five occlusions with consistent shape of mouth pressure–time curves was taken to be a Rint measurement. To assess feasibility the children were categorized as ‘satisfactory’, ‘failure’ and ‘rejected’ depending on the outcome of the test. Outcome variables were respiratory symptoms score and Rint. Satisfactory Rint measurement was obtained in 46 (61%) children, 9 (36%) 2-year olds, 17 (65%) 3-year olds and 20 (80%) 4-year olds. As compared with the preterm control children (n=18), CLD children (n=28) had significantly higher respiratory symptoms score (18.5 vs 6, P |
| Databáze: | OpenAIRE |
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