Association of chest compression pause duration prior to E-CPR cannulation with cardiac arrest survival outcomes

Autor: Kasper G. Lauridsen, Javier J. Lasa, Tia T. Raymond, Priscilla Yu, Dana Niles, Robert M. Sutton, Ryan W. Morgan, Mary Fran Hazinski, Heather Griffis, Richard Hanna, Xuemei Zhang, Robert A. Berg, Vinay M. Nadkarni, Kamal Abulebda, Diane Atkins, Shilpa Balikai, Marc Berg, Robert Berg, Utpal Bhalala, Matthew S. Braga, Corinne Buysse, Adam Cheng, Andrea Christoff, Kelly Corbett, Allan DeCaen, Katherine Daniels, Gabry deJong, Jimena del Castillo, Maya Dewan, Aaron Donoghue, Ivie Esangbedo, Michael Flaherty, Stuart Friess, Sandeep Gangadharan, Orsola Gawronski, Jonathan Gilleland, James Gray, Helen Harvey, Ilana Harwayne-Gidansky, Sarah Haskell, Jennifer Hayes, Kiran Heber, Betsy Hunt, Takanari Ikeyama, Priti Jani, Monica Kleinman, Lynda Knight, Hiroshi Kurosawa, Kasper Glerup Lauridsen, Tara Lemoine, Tensing Maa, Elizabeth Masse, Luz Marina Mejia, Yee Hui Mok, Ryan Morgan, Vinay Nadkarni, Sholeen Nett, Amanda O'Halloran, Michelle Olson, Gene Ong, Prakad Rajapreyar, Tia Raymond, Joan Roberts, Anita Sen, Sophie Skellet, Daniel Stromberg, Felice Su, Robert Sutton, Todd Sweberg, Oscar Tegg, Ken Tegtmeyer, Alexis Topjian, Wendy Van Ittersum, Javier Urbano Villaescusa, Ichiro Watanabe, Denise Welsby, Jesse Wenger, Heather Wolfe, Andrea Yeo, Pricilla Yu
Přispěvatelé: Pediatric Surgery
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Resuscitation, 177, 85-92. Elsevier Ireland Ltd
Glerup Lauridsen, K, Lasa, J J, Raymond, T T, Yu, P, Niles, D, Sutton, R M, Morgan, R W, Fran Hazinski, M, Griffis, H, Hanna, R, Zhang, X, Berg, R A, Nadkarni, V M & PediRES-Q Investigators 2022, ' Association of Chest Compression Pause Duration Prior to E-CPR Cannulation with Cardiac Arrest Survival Outcomes ', Resuscitation, vol. 177, pp. 85-92 . https://doi.org/10.1016/j.resuscitation.2022.05.004
ISSN: 0300-9572
DOI: 10.1016/j.resuscitation.2022.05.004
Popis: OBJECTIVE: To characterize chest compression (CC) pause duration during the last 5 minutes of pediatric cardiopulmonary resuscitation (CPR) prior to extracorporeal-CPR (E-CPR) cannulation and the association with survival outcomes.METHODS: Cohort study from a resuscitation quality collaborative including pediatric E-CPR cardiac arrest events ≥10 min with CPR quality data. We characterized CC interruptions during the last 5 min of defibrillator-electrode recorded CPR (prior to cannulation) and assessed the association between the longest CC pause duration and survival outcomes using multivariable logistic regression.RESULTS: Of 49 E-CPR events, median age was 2.0 [Q1, Q3: 0.6, 6.6] years, 55% (27/49) survived to hospital discharge and 18/49 (37%) with favorable neurological outcome. Median duration of CPR was 51 [43, 69] min. During the last 5 min of recorded CPR prior to cannulation, median duration of the longest CC pause was 14.0 [6.3, 29.4] sec: 66% >10 sec, 25% >29 sec, 14% >60 sec, and longest pause 168 sec. Following planned adjustment for known confounders of age and CPR duration, each 5-sec increase in longest CC pause duration was associated with lower odds of survival to hospital discharge [adjusted OR 0.89, 95%CI: 0.79-0.99] and lower odds of survival with favorable neurological outcome [adjusted OR 0.77, 95%CI: 0.60-0.98].CONCLUSIONS: Long CC pauses were common during the last 5 min of recorded CPR prior to E-CPR cannulation. Following adjustment for age and CPR duration, each 5-second incremental increase in longest CC pause duration was associated with significantly decreased rates of survival and favorable neurological outcome.
Databáze: OpenAIRE
Externí odkaz: