Radical radiotherapy for metachronous oligometastasis after initial treatment of esophageal cancer
| Autor: | Gang Feng, Lidan Geng, Xiaobo Du, Tangzhi Dai, Huan Du, Xiyue Yang, Zhongzheng Xiang, Lei Liu, Jie Li, Yixue Wen, Yu Zhang, Jie Bai |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Lung Neoplasms Esophageal Neoplasms medicine.medical_treatment Radiosurgery Effective dose (radiation) Gastroenterology 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Clinical endpoint Humans Radiology Nuclear Medicine and imaging Retrospective Studies business.industry Hazard ratio Hematology Chemoradiotherapy Esophageal cancer medicine.disease Confidence interval Radiation therapy Treatment Outcome Oncology 030220 oncology & carcinogenesis Radiotherapy Intensity-Modulated business |
| Zdroj: | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 154 |
| ISSN: | 1879-0887 |
| Popis: | BACKGROUND AND PURPOSE This study aimed to evaluate the efficacy of radical radiotherapy and assess prognostic factors in metachronous oligometastatic esophageal cancer (MOEC) patients after initial treatment with curative-intent surgery and/or chemoradiotherapy. MATERIALS AND METHODS MOEC Patients during 2009-2018 in Mianyang Central Hospital were retrospectively analyzed. Each patient had ≤5 oligometastatic lesions, and the primary lesions were controlled in this study. Patients were devided into radiotherapy (RT) and non-radiotherapy (NRT) groups. The study endpoints were overall survival (OS) and treatment toxicities. RESULTS This study included 82 patients who underwent intensity-modulated radiotherapy for MOEC. Median OS were 14 (95% confidence interval [CI], 11.0-17.0) and 7 (95% CI, 4.5-9.5) months for the RT and NRT groups, respectively (P = 0.016). Median OS were 18 (95% CI, 13.6-22.4) and 10 (95% CI, 5.1-14.9) months for lung and bone metastases, respectively (P = 0.010). Median OS were 15 (95% CI, 12.4-17.6) and 10 (95% CI, 7.6-12.4) months for interval time from initial diagnosis to metastasis ≥12 and |
| Databáze: | OpenAIRE |
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