Chitosan Hydrogels and Bionanocomposites Formed through the Mineralization and Regulated Charging
| Autor: | Yury Shchipunov, Vladimir Silant'ev, Sergei Sarin, Irina Postnova |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Biocompatibility General Chemical Engineering technology industry and agriculture Cationic polymerization Nanoparticle macromolecular substances 02 engineering and technology General Chemistry Mineralization (soil science) 010402 general chemistry 021001 nanoscience & nanotechnology Polysaccharide 01 natural sciences Biochemistry Polyelectrolyte 0104 chemical sciences Chitosan chemistry.chemical_compound chemistry Chemical engineering Self-healing hydrogels Materials Chemistry 0210 nano-technology |
| Zdroj: | Chemical record (New York, N.Y.). |
| ISSN: | 1528-0691 |
| Popis: | The account presents survey of our systematic studies on chitosan. Only this polysaccharide bears cationic charges, possesses antimicrobial activity and wound healing ability that make it highly appropriate for using in medicine, biomedical engineering, cosmetics, food, packaging. However, its application meets with severe limitation. Chitosan belongs to polysaccharides that do not jellify solutions. Main approaches are based on the chemical modifications and cross-linking, but these treatments impairs therewith the biocompatibility and biological activity of chitosan. We have developed approaches in which monolithic hydrogels are fabricated via the mineralization of polysaccharide by method of green sol-gel chemistry and via the formation of polyelectrolyte complex with oppositely charged counterparts in the regime of its charging by means of regulated acidification. The latter approach was also extended for the preparation of chitosan bionanocomposites and films with nanoparticles. |
| Databáze: | OpenAIRE |
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