Intestinal-type Adenocarcinoma Presenting as a Mandibular Mass: An Unusual Presentation
| Autor: | Ashi Chug, Nouman Rashid, Adity Bansal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Periosteal reaction Orthodontics Case Report Adenocarcinoma Malignancy Metastasis Cytokeratin Carcinoembryonic antigen intestinal adenocarcinoma medicine metastasis biology business.industry Mediastinum medicine.disease lcsh:RK1-715 medicine.anatomical_structure lcsh:Dentistry biology.protein Periodontics Abdomen Oral Surgery mandibular metastasis business |
| Zdroj: | Contemporary Clinical Dentistry Contemporary Clinical Dentistry, Vol 12, Iss 1, Pp 99-101 (2021) |
| ISSN: | 0976-2361 0976-237X |
| Popis: | Intestinal-type adenocarcinoma is an aggressive malignancy with the rare possibility of metastatic spread to the mandible. We represent a case of a 30-year-old female patient who reported with a chief complaint of a right mandibular mass for 4 months. Orthopantomogram X-ray observed an ill-defined lytic lesion with severe periosteal reaction. Incisional biopsy revealed “colonic variant of intestinal-type adenocarcinoma.” Expression of cytokeratin 20 and caudal type homeobox transcription factor 2 (CDX-2) markers was seen on immunohistochemistry. Biochemical markers such as serum cancer antigen 125, serum alkaline phosphatase, and serum carcinoembryonic antigen were raised. Contrast-enhanced computed tomography of the thorax and abdomen suggested cavitary lesions in the bilateral lungs, right adrenal gland, and mediastinum. Positron emission tomography revealed multiple lesions in the body, hence confirming the diagnosis. The patient was kept on palliative chemotherapy. It is concluded that prompt diagnosis and initiation of treatment increases the chances of survival in such cases. |
| Databáze: | OpenAIRE |
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