Prevalence of Auditory Neuropathy: Prospective Study in a Tertiary-Care Center
| Autor: | Francisco Rodríguez Domínguez, Nieves Cañizares Gallardo, Rafael Pérez Aguilera, José Domingo Cubillana Herrero |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Hearing loss Hearing Loss Sensorineural Auditory neuropathy Population Audiology Tertiary care Screening programme Prevalence Vestibulocochlear Nerve Diseases medicine Humans Prospective Studies Prospective cohort study education Cochlear Nerve education.field_of_study business.industry Infant General Medicine medicine.disease Auditory brainstem response Female Sensorineural hearing loss medicine.symptom business |
| Zdroj: | Acta Otorrinolaringologica (English Edition). 58:239-245 |
| ISSN: | 2173-5735 |
| DOI: | 10.1016/s2173-5735(07)70342-3 |
| Popis: | Objective The primary goal of this study is to determine the frequency of onset of this disorder in our infant population. Its clinical importance is due, among other reasons, to the fact that idiopathic cases constitute false negatives in the auditory screening programmes based on the performance of otoacoustic emissions to all newborn children and brainstem auditory evoked response only to those presenting these risk factors, for which reason another goal is to establish the prevalence of these pure cases and the diagnostic delay they cause. Patients and method Prospective study of all newborn children at the Virgen de la Arrixaca Mother and Child Hospital (Murcia, Spain) in the period between June 1, 2000 and June 30, 2006. Results Our screening programme, with a coverage of 95.68%, detected 114 patients with unilateral or bilateral sensorineural hearing loss, with 6 presenting hearing loss attributable to auditory neuropathy. Conclusions The estimated prevalence of auditory neuropathy in our infant population turned out to be 1.406 for every 10 000 children, ie 5.26% of all sensorineural hearing loss diagnosed. Another significant finding was the delay in diagnosis, since the mean age at the moment of diagnosis was of 11.5 months, mainly due to idiopathic cases not detected during neonatal screening. Two clear conclusions can be inferred from these data: a) auditory neuropathy does not constitute an extraordinarily rare disorder, and b) idiopathic cases constitute false negatives in the universal auditory screening programmes based on the performance of otoacoustic emissions, which habitually leads to a delay in diagnosis and treatment. |
| Databáze: | OpenAIRE |
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