Cerebral venous and sinus thrombosis with cerebrospinal fluid circulation block after the first methotrexate administration by lumbar puncture
| Autor: | M. J. van den Bent, P.J. Voogt, H.P. Bienfait, J.M.M. Gijtenbeek, H. G. de Bruin, M. Pillay |
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| Přispěvatelé: | Neurology, Radiology & Nuclear Medicine, Hematology |
| Rok vydání: | 2002 |
| Předmět: |
Male
musculoskeletal diseases medicine.medical_specialty Antimetabolites Antineoplastic Pathofysiologie van Hersenen en Gedrag Pathophysiology of Brain and Behaviour Spinal Puncture Dexamethasone Central nervous system disease Route of administration medicine Humans Radiology Nuclear Medicine and imaging Sagittal Sinus Thrombosis Glucocorticoids Cerebrospinal Fluid medicine.diagnostic_test Lumbar puncture business.industry Vascular disease Heparin Middle Aged medicine.disease Thrombosis Leukemia Lymphocytic Chronic B-Cell Magnetic Resonance Imaging Surgery Methotrexate Anesthesia Cerebrospinal fluid circulation Drug Therapy Combination Neurology (clinical) Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Neuroradiology, 44, 929-32 Neuroradiology, 44, 11, pp. 929-32 Neuroradiology, 44, 929-932. Springer-Verlag |
| ISSN: | 1432-1920 0028-3940 |
| DOI: | 10.1007/s00234-002-0854-3 |
| Popis: | Item does not contain fulltext We report a patient treated for small lymphocytic lymphoma/leukemia with cerebral venous and sinus thrombosis (CVST) after lumbar puncture with intrathecal administration of methotrexate (MTX). He also developed a cerebrospinal fluid flow block. This is the first report of an association between lumbar puncture and intrathecally administered MTX and the development of CVST. Intrathecal treatment in this patient was discontinued and he was successfully treated with high-dose low-molecular-weight heparin subcutaneously. |
| Databáze: | OpenAIRE |
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