Targeting the Jak/Signal Transducer and Activator of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa–Squamous Cell Carcinoma
Autor: | J. Jackow, David Alvarez Cespedes, David M. Owens, Angela M. Christiano, Rolando Perez-Lorenzo, Corey Hansen, Avina Rami, Alberto Pappalardo, D. Delorenzo, Zongyou Guo, Arianna L. Kim, R. Hayashi |
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Rok vydání: | 2021 |
Předmět: |
STAT3 Transcription Factor
Ruxolitinib Collagen Type VII Skin Neoplasms Cutaneous squamous cell carcinoma Administration Oral Dermatology Biochemistry stat Mice Cell Line Tumor Nitriles Recessive dystrophic epidermolysis bullosa Animals Humans Medicine Basal cell Molecular Biology Janus Kinases business.industry Cell Biology Fibroblasts Xenograft Model Antitumor Assays Epidermolysis Bullosa Dystrophica Pyrimidines Mutation Carcinoma Squamous Cell STAT protein Cancer research Pyrazoles business Signal Transduction medicine.drug |
Zdroj: | Journal of Investigative Dermatology. 141:942-946 |
ISSN: | 0022-202X |
Databáze: | OpenAIRE |
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